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KMID : 0613820180280070795
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Journal of Life Science
2018 Volume.28 No. 7 p.795 ~ p.801
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Association of SNP Markers on Chromosomes 3 and 9 with Body Weight in Jeju Horses
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Kim Nam-Young
Yang Young-Hoon
Park Nam-Geon
Yang Byoung-Chul
Son Jun-Kyu
Shin Sang-Min
Woo Jae-Hoon
Shin Moon-Cheol
Yoo Ji-Hyun
Hong Hyun-Ju
Park Hee-Bok
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Abstract
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This study was conducted to investigate the association of single nucleotide polymorphism (SNP) markers on equine chromosomes (ECA) 3 and 9 with body weight in Jeju horses. We used DNA samples and body weight data of 320 horses provided by the Livestock Promotion Agency, Jeju Special Self-Governing Province, and the Korean Racing Association, respectively. We genotyped all the experimental animals using nine SNP markers located on ECA 3 (BIEC2-808466, BIEC2-808543, BIEC2- 808967, and BIEC2-809370) and ECA 9 (BIEC2-1105370, BIEC2-1105372, BIEC2-1105377, BIEC21105505, and BIEC2-1105840). These markers were selected due to their effects on body conformation traits in horses. The joint effect of the genotypes of the two SNP markers (BIEC2-808467 and BIEC2-1105377) regarding body weight were also evaluated. The estimated breeding value (EBV) of body weight was obtained as the dependent variable for association analyses using a linear mixed model. Significant associations were detected between SNP markers (BIEC2-808543, BIEC2-808967, BIEC2-809370, BIEC2- 1105370, BIEC2-1105372, and BIEC2-1105377) and the body weight EBV. In addition, the joint genotype effect of the BIEC2-808467 and BIEC2-1105377 on the body weight EBV was significant. These results indicate that the SNP markers, which showed their significant effects on body conformation, can be used as genetic markers to improve the efficiency of the selective breeding program for the body weight traits in Jeju horses.
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KEYWORD
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Association, body weight, Jeju horses, SNP markers
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